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But that monumental day is coming. At first, genome editing will be used to eliminate hereditary diseases, such as sickle cell anemia, cystic fibrosis, and hemochromatosis (excessive iron in the blood), and to eliminate predispositions to diseases like cancer, heart disease, behavioral disorders, and dementia. Eventually, genome editing will be used to treat less serious conditions, such as male pattern baldness, or to select a child’s hair and eye color. More radically, germline interventions could be used for enhancement purposes and the introduction of super-human characteristics, such as greater memory and intelligence, super-robust immune systems (e.g. a built-in immunity to AIDS or bacterial superbugs), and greater physical strength. In theory, genomic editing could also be used to introduce new characteristics altogether, such as an increased dynamic acoustic range, an ability to see infrared and ultraviolet light, and the ability to hold breath underwater for extended periods.

The Nuffield Council on Bioethics did not explicitly address some of these more futuristic scenarios, but the language in report did not preclude these possibilities. To be deemed ethical, the council said heritable genome editing interventions must adhere to two overarching principles: They “must be intended to secure, and be consistent with, the welfare of the future person,” and “they should not increase disadvantage, discrimination or division in society,” write the authors of the report.

The council also made a batch of recommendations: Genome tweaks should be licensed on a case-by-case basis; more research is needed to establish standards of clinical safety; long-term studies should assess potential risks to individuals, groups, and society as as whole; and so on. The council also wants to see the establishment of an independent UK body to promote public debate on the matter, and to monitor social, cultural, legal, and health impacts. The UK should also work with international organizations, such as UNESCO and the Council of Europe, to establish a framework for international governance on these treatments.

“Whilst there is still uncertainty over the sorts of things genome editing might be able to achieve, or how widely its use might spread, we have concluded that the potential use of genome editing to influence the characteristics of future generations is not unacceptable in itself. However, the possibilities it raises could have significant impacts on individuals, families and on society,” said Yeung. “It is important that governments and public authorities step up and address these possibilities before people start asking to use this technology. Therefore, we urge the government to invest in supporting and encouraging broad and inclusive public debate, and put in place the governance measures that we need to ensure this promising technology is not used against the public interest.”

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Last week’s historic summit on human gene-editing has come to a close, and its organizing committee …

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Today’s report is good for the United Kingdom, but it’s also good for the world. In addition to normalizing the conversation around gene modification, the Nuffield Council on Bioethics is providing a sensible and responsible roadmap for moving forward. It’s still early days, but this is a great start.


When legal matters.

Antoinette Theodossakos

Antoinette guides employers – from large companies with many locations to start-up enterprises with one office and a few employees – in all aspects of labor relations and employment-related issues in the workplace. She has experience in federal and state courts as well as before agencies such as the Florida Commission on Human Relations and the Equal Employment Opportunity Commission.

Antoinette advises clients in a broad range of employment issues including employment terminations, sexual harassment, racial and gender investigations, and family and medical leave.

Born in Ontario, Canada, Antoinette grew up in West Palm Beach. She received her law degree from Northeastern University School of Law, Boston and a master’s degree from Florida Atlantic University. While in law school at Northeastern, Antoinette was a member of the Moot Court Team; and at FAU, she was a member of the Alpha Kappa Delta National Sociology Honor Society.

Prior to joining Haile Shaw Pfaffenberger, Antoinette was a partner with Edwards Angell Palmer Dodge, LLP, now known as Locke Lord.

She is a member of the Florida Bar and the Palm Beach County Bar Association. Antoinette is the vice chair of the Palm Beach State College Foundation, a member of the Society for Human Resource Management, a former board member of Nonprofits First, and a former member of the Leukemia Lymphoma Society’s Team-in-Training.

Antoinette frequently speaks to organizations and has published articles on employment law and related current topics.

Haile Shaw Pfaffenberger – When Legal Matters.

As a kid, Antoinette did her homework sitting at a table in her family’s restaurant – Howley’s, a West Palm Beach landmark. Her experience both learning and working at Howley’s helped pave the way toward Antoinette’s keen skills in employment law. Today, Antoinette brings her own children to the restaurant which their grandparents sold some years ago. In her spare time, she enjoys running and cycling, and has completed two marathons, five sprint-distance triathlons and three Olympic-distance triathlons on behalf of the Leukemia Lymphoma Society of Palm Beach County.

Corporate Business

Antoinette Theodossakos

Shareholder [email protected]

EDUCATION Northeastern University School of Law Florida Atlantic University

PRACTICE AREAS Corporate Business Employment Litigation Nonprofit

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Magnifico (Printed Diapers)
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35 Reviews Add Your Review

Bambino Magnifico Diapers are the most absorbent and comfortable diapers yet! Features our first all over print, patent pending stretch waist technology for the perfect fit and hybrid diaper construction. The new gold standard for ABDL diapers!

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Magnifico We are proud to introduce the new gold standard for ABDL diapers - The Bambino Magnifico! They are the most absorbent and comfortable diapers the community has ever seen. They have an all over print and incorporate our patent pending stretch waist technology for the perfect fit. Their unique hybrid diaper construction and unmatched comfort will make you never want to take them off or wear another diaper ever again! We have worked hard on bringing this diaper to life for over a year now, involving the ABDL community every step of the way! From feedback on the original prototype diapers (we listened and improved them!) to the naming contest and artwork contest. We couldn't be happier with the results and can't wait for everyone to experience what a premium adult diaper should be. Enjoy!


The important details you need to know:

Our first all over print featuring a cute, unisex dino design! Patent pending stretch waist panel with micro memory technology All plastic diaper with mechanical hook and loop closure system More absorbent and comfortable than our Bellissimo Newly designed extra wide, extra strength hook tabs Hybrid sizing! S/M - 26"-46" waist, L/XL - 36"-56" waist
ATTENTION: Oils/Lotions/Creams can cause ink to skin transmission on plastic diapers. We do not cover damages if this occurs.
Reviews 35
Customer Reviews
Show per page
The Love Affair Continues
I've been wearing these diapers since they came out, and my addiction to them is getting stronger. They hug like no other diaper, and feel incredible on me, wet or dry. Expensive, but I am powerless to resist them! Watch for sales, always buy full cases, cut back in other areas, and you can afford to wear Magnificos, the best diaper of all. Once you start wearing them you will never be able to stop!

Review by DiaperMike

Posted on

Wow what an awesome diaper
This is fantastic such a comfortable Diaper. Im really impressed we'll worth the money I just wish it would make more noise.

Review by Snakeyees

Posted on

Most comfy diapers ever!
I was on the fence about trying these and I am glad I did the diapers are awesome perfect for day or night time use. Can't wait for my little girl to try them this weekend cause these are the best diapers I've ever worn. I love being able to readjust the tabs as needed and the stretchy sides make day time use at work comfortable and easy. Definitely found my new #1 diaper.

Review by DL_daddt

Posted on

Really good diaper!
I just bought the sample to try and it fits real good, the stretch is really nice and snug, had no issues with it at all. The stretch makes bending and stuff feel a lot better than the other diapers too, will definitely be buying some more and the print is nice too!!! Would recommend :)

Review by Johnny

Posted on

#1 Diaper
I like to pee alot as a 210lb 5'8" man. This Diaper fits my 41" waist perfectly. I'm not that slim, BUT these diapers fit PERFECT! They are a dream DIAPER! THEY ADJUST! They don't need tape! They stretch. They are soft. I hope they make the same diaper with different print. I like cute diapers with animals, or other cute objects.

Review by Zeek

Posted on

Nothing else compares
I was blown away when I got my case last week. This diaper is the best...the stretch,and the velcro tabs are the best thing ever. If you don't have these diapers then you have second rate or third rate diapers. These are the best ever. Thanks Bambino

Review by Diaper John

Posted on

this diapers are the best ever!
I have been in incontinence briefs for over 6 years, I'm pretty confident I have tried every "advanced" type of Diaper there available. Hands down these are the best I have EVER worn, They excel in both fit and comfort. The new tab system is absolutely awesome. Simply speaking i've never been happier with a diaper.......!

Review by Jeffery

Posted on

Very Comfy!
I just got my case of these diapers and I love them. There Super cute and nice and thick and padded. There fun to wear and pretty cute when wet because it kinda makes me walk more baby like because of the then more thickened crotch and back padding becomes. Also I absolutely love the stretch waist and the way the diaper fastens around your waist and how absorbent they are. These hold very secure and are very comfy to sleep in and wake up to. The small/medium is a little bigger then I thought it would be but Im not complaining this diaper gets 5 stars from me. Thank you for making such a great diaper. Love BabyGirlKat.

Review by BabyGirlKat

Posted on

Second to nobody now in the niche specialty diaper makers
So I’ve never worn a Bambino diaper in my 31 years of dealing with 24/7 urinary and at times bowel incontinence. Not sure why I even ordered a half case of these diapers recently. It was on an impulse for sure having just added two cases of my favorite all time night diaper “Rearz Safari” to my shopping cart. This being since wife/Mommy halted my use of cloth diapers 24/7 for most of the past 10 years. So I get these very ABDL diapers and decide to wear for daytime use. Hesitant at first to go to far with the tap tab system having been burned over and over again with tab migration, pop-offs, and poked in the upper thighs too. Over the next two days I push both the tape tabs and duration before changing till I reach that all too familiar “saturation point” where I dare not sit down least I have the frown faces of shame and wetness on my backside for all to see. Next I realize the diaper is noteworthy for absorbency. This is good but what I’m about to share is genuine pure honesty. I’ve never worn a diaper that fits as well, felt as though normal underwear, and was super discreet. My God this is such an incredible diaper and it is dynamic with bending sitting etc....without the usual worries of all prior disposable specialty diapers I’ve worn for 31 years. Can’t say enough great things here and now regret never having tried Bambino diapers till know! There’s a new boss in town and it’s Bambino Magnificio Dino with stretch tape tabs. I will be sharing this with all my friends and patients that I know who suffer from chronic incontinence. This is the best and thanks so very much!

Review by Pisspants

Posted on

greatest nappie ever
these are the best diapers I have ever worn and the tabs to fasten it are the best!

Review by lil sissy

Posted on

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If you want to challenge the Penalty Charge Notice (PCN) then you have 28 days from the date of service of the PCN to get your representation to us.

Under the Interpretation Act 1978 s.7, unless the contrary is proved, service is deemed to have been effected at the time when the PCN would be delivered in the ordinary course of post.

Representations must be made in writing or online.

If you make a representation outside of the 28-day PCN service period it will be considered as 'late' and we do not have to consider late representations. You cannot make a late representation online.

You can now make a representation online. You will need to provide us with your PCN number and reasons why you think you should not have been issued with a PCN. You will also be able to add supporting evidence.

You still have 28 days from the date of service of the PCN, to either pay the penalty or challenge the PCN by making a representation. The PCN states the full penalty charge due - however, if you pay within 14 days of the date of service, you can pay the 50% discount sum stated on the PCN.

Make a representation

In writing

The easiest way to make a representation in writing is to complete the representation section provided as part of the PCN:

The registered keeper

The PCN is normally sent to the registered keeper of the vehicle as per the records of either the or DVANI .

PCNs may also be issued to the nominated hirer/lessee of the vehicle if a valid hire agreement is provided by the registered keeper.

It is the person or organisation named on the PCN who must make the representation, even if they were not the driver.

Our response

When we have considered your representation we will write back to you with our response. You will be sent one of three things:

A request for additional evidence

A notice of acceptance

A notice of rejection

Grounds for making a representation

A representation may be made on one of six grounds, or if none of these are applicable you may state the reasons why you do not believe that you are liable for the PCN.

Each ground for representation is defined by Parliament in the regulations governing Congestion Charging.

By clicking on each number below you can find out about each ground, the evidence you need to provide and the circumstances that are applicable. This does not affect your right to make a representation but is a guide to assist you.

Remember,it is for you to prove that you meet any of these grounds.

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Risk Warning: Trading Contracts For Difference and Foreign Exchange is highly speculative and carries a level of risk that may not be suitable for all investors. You may lose some or all of your invested capital; therefore, you should not speculate with the capital you cannot afford to lose. You should be aware of all the risks associated with trading Contracts For Difference and Foreign Exchange. Please ensure you read our Terms and Conditions and Risk Disclosure Statement before making any operation on our trading platform. We reserve our rights to cancel all or a single client deal in case of front-running or any other suspicious activity without a preliminary notification. KayaFX is owned and operated by GammaTech Services OÜ, Roosikrantsi 2-K284, Tallinn, Harju maakond, 10119. © All Rights Reserved. KayaFX 2018.
Risiko-Warnung: Das Handeln mit Contracts For Difference und Devisen ist hoch spekulativ und birgt ein Risiko, das möglicherweise nicht für alle Anleger geeignet ist. Sie können ein Teil oder ihr gesamtes investiertes Kapital verlieren; Spekulieren sie also nicht mit Kapital, wenn der Verlust für Sie eine schwere finanzielle Schädigung darstellen würde. Sie sollten sich aller Risiken im Zusammenhang mit dem Handel mit Contracts For Difference und Devisen bewusst sein. Bitte stellen Sie sicher, dass Sie unsere Allgemeinen Geschäftsbedingungen und die Risikohinweise gelesen haben, bevor Sie auf unserer Handelsplattform tätig werden. Wir behalten uns das Recht vor, alle oder einen Kundenvertrag im Falle von Front-Run oder einer anderen verdächtigen Tätigkeit ohne vorherige Benachrichtigung zu stornieren. KayaFX gehört und wird betrieben von GammaTech Services OÜ, Roosikrantsi 2-K284, Tallinn, Harju maakond, 10119. © Alle Rechte vorbehalten. KayaFX 2018.
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Aviso de Risco: a negociação de Contratos Por Diferença e de Câmbio de Moeda Estrangeira (Forex) é altamente especulativa e envolve um nível de risco que pode não ser adequado para todos os investidores. Você pode perder parte ou todo seu capital investido; sendo assim, você não deve especular com capital que você não pode perder. Você deverá estar ciente de todos os riscos relacionados às negociações de Contratos Por Diferença e Câmbio Estrangeiro. Por favor, não deixe de ler nossos Termos e Condições e a Declaração de Divulgação de Risco antes de fazer qualquer operação na nossa plataforma. Nós nos reservamos o direito de cancelar, sem prévio aviso, todos ou um único cliente em atividades de obtenção antecipada de informações privilegiadas ou quaisquer outras atividades suspeitas. KayaFX é de propriedade e operada por GammaTech Services OÜ, Roosikrantsi 2-K284, Tallinn, Harju maakond, 10119. © Todos os Direitos Reservados. KayaFX 2018.